Dyslipidemia with Cardiovascular Disease (CVD)


CVD is the most common health problem worldwide. This disease is often manifested as coronary heart disease (CHD). According to the international reports, mortality of CHD in the developed countries is expected to reach almost 29 percent in women and 48 percent in men in years 1990-2020.

Lipids (fats), together with proteins and carbohydrates, are the main components of living cells. Cholesterol and triglycerides are lipids that are stored in the body and serve as a source of energy.

Desirable levels of blood fats are:

Total cholesterol: Below 200 mg/dL

HDL cholesterol: Men – above 40 mg/dL; Women – above 50 mg/dL

LDL cholesterol: Below 100 mg/dL; Below 70 mg/dL for people with diabetes or heart disease.

Triglycerides: Below 150 mg/dL

*The Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III, or ATP III)

When lipid levels in the bloodstream are too high or low, this condition is called dyslipidemia. The most common types of dyslipidemia are:

High levels of low-density lipoprotein (LDL or “bad”) cholesterol

Low levels of high-density lipoprotein (HDL or “good”) cholesterol

High levels of triglycerides

When LDL cholesterol levels are high, fatty deposits (called plaques) can build up in the arteries, the blood vessels that carry blood from the heart throughout the body. Over time, plaques narrow the arteries, producing atherosclerosis (hardening of the arteries). This can cause heart disease, heart attack, peripheral artery disease (reduced blood flow in the limbs, usually the legs), or stroke. Low levels of HDL and high levels of triglycerides can also increase fat build-up in the arteries.

Two main sources of cholesterol exist: One is dietary intake and the other is endogenous hepatic production. Lifestyle changes, such as increased physical activity, healthy diet, and reduced caloric intake, have been associated with reducing the risk to get CVD.

Recently, there is a clinical study to investigate the health benefits of rich natural mineral water to reduce total cholesterol level dan LDL-C in men suffering from high cholesterol. Ardesy as a rich natural sparkling mineral water contains of high minerals that could have benefits for health and wellness. Sodium bicarbonate found in Ardesy has been suggested to lower LDL-C. This was suggested by The Journal Nutrition and the clinical study that was conducted both by myself in Jakarta and my colleagues, Dr Kho in Singapore’s Hospital, if drinking Ardesy 1 L/day for 1 month, could significantly reduced total cholesterol level (p=.0026) and LDL-C (p<.0001).

 

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